Cities Facing Increased Rat and Mice Populations in 2025

According to the NPMA’s Public Health Pest Index, changing weather patterns are contributing to increased rodent activity in several U.S. cities. Severe winter conditions, including extreme cold, heavy snowfall, and fluctuating temperatures, are driving rodents indoors in search of warmth, food, and shelter. This trend is expected to cause a surge in infestations across both residential and commercial properties.

9 Cities Expected to Be Most Affected by Rodent Activity in Winter and Spring 2025

As winter intensifies, rodents are increasingly seeking refuge indoors. Here are the cities most impacted by this shift:

Boston, MA

Intense snowstorms and freezing temperatures will drive rodents indoors in search of shelter.

Denver, CO

A long, freezing winter filled with heavy snowfall is driving mice indoors, with white-footed mice among the species seeking refuge in residential and commercial buildings.

Florida

The extreme cold, especially in northern Florida, has driven rodents indoors as they seek warmth and protection from the harsh conditions.

Grand Rapids, MI

Unprecedented snowfall is forcing rats and mice to escape the cold by invading homes and businesses.

Louisville, KY

Record-breaking cold and snowfall have made indoor spaces attractive havens for rats and mice looking for warmth and sustenance.

New Orleans, LA

The region's unprecedented snowfall has likely driven rats indoors, seeking warmth and refuge from the severe winter conditions.

Salt Lake City, UT

House mice, including white-footed mice, are being driven indoors due to freezing temperatures, seeking warmth and reliable water sources.

Seattle, WA

A mild and dry start to winter has encouraged rodents to move indoors earlier than usual.

Washington, DC

Extreme temperature swings have led to a notable increase in rodent activity across the city.

The Growing Concern of Rodent Infestations

Each year, rodents invade an estimated 21 million homes in the U.S., with the majority of infestations occurring in the colder months. These pests not only cause structural damage by gnawing through wires, pipes, and insulation, but also pose significant health risks by contaminating food and spreading diseases such as Salmonella, Hantavirus, and Rat-Bite Fever.

How to Protect Your Home from Rodents

Rodents can enter homes through small openings—mice can squeeze through holes as small as a dime, while rats can fit through spaces the size of a quarter. To prevent rodent infestations:

• Seal entry points – Close cracks and gaps around doors, windows, and foundations.
• Improve drainage – Ensure water is diverted away from the home with gutters and downspouts.
• Eliminate food sources – Store food in airtight containers and avoid leaving pet food out overnight.
• Declutter storage areas – Keep basements, attics, and garages clean and organized.
• Inspect regularly – Look for signs of rodent activity such as droppings, chewed wires, and nesting materials.

Find Rodent Control Services Near You

If you suspect a rodent infestation, find a pest control professional in your area before attempting DIY solutions to ensure effective and lasting rodent control.